Behavioral Neuroepigenetics Lab

PUBLICATIONS

papers list
69	Distinct prefrontal projection activity and transcriptional state conversely orchestrate social competition and hierarchy Tae-Yong Choi, Hyoungseok Jeon, Sejin Jeong, Eum Ji Kim, Jeongseop Kim, Yun Ha Jeong, Byungsoo Kang, Murim Choi, Ja Wook Koo [Neuron (2024) ] Abstract
68	Synaptotagmin-4 induces anhedonic responses to chronic stress via BDNF signaling in the medial prefrontal cortex Jeongseop Kim, Sihwan Seol, Tae-Eun Kim, Joonhee Lee, Ja Wook Koo, Hyo Jung Kang [Exp Mol Med (2024) ] Abstract
67	Parietal-Frontal Pathway Controls Relapse of Fear Memory in a Novel Context Bitna Joo, Shijie Xu, Hyungju Park, Kipom Kim, Jong-Cheol Rah, Ja Wook Koo [Biol Psychiatry Glob Open Sci (2024) ] Abstract
66	Mesocorticolimbic circuit mechanisms of social dominance behavior Tae-Yong Choi, Sejin Jeong, Ja Wook Koo [Exp Mol Med (2024) ] Abstract
65	The Role of Glutamate Underlying Treatment-resistant Depression Jeongseop Kim, Tae-Eun Kim, Seung-Hwan Lee, Ja Wook Koo [Clin Psychopharmacol Neurosci (2023) ] Abstract
64	Lactobacillus reuteri ATG-F4 Alleviates Chronic Stress-induced Anhedonia by Modulating the Prefrontal Serotonergic System Jiyun Lee, Eum-Ji Kim, Gun-Seok Park, Jeongseop Kim, Tae-Eun Kim, Yoo Jin Lee, Juyi Park, Jihee Kang, Ja Wook Koo, Tae-Yong Choi [Exp Neurobiol (2023) ] Abstract
63	Synaptic ensembles between raphe and D1R-containing accumbens shell neurons underlie postisolation sociability in males Ja Eun Choi, Dong Il Choi, Jisu Lee, Jooyoung Kim, Min Jung Kim, Ilgang Hong, Hyunsu Jung, Yongmin Sung, Ji-Il Kim, TaeHyun Kim, Nam-Kyung Yu, Seung-Hee Lee, Han Kyoung Choe, Ja Wook Koo, Joung-Hun Kim, Bong-Kiun Kaang [Sci Adv (2022) ] Abstract
62	Corrigendum: Problematic Use of Alcohol and Online Gaming as Coping Strategies During the COVID-19 Pandemic: A Mini Review Shijie Xu, Minkyung Park, Ung Gu Kang, Jung-Seok Choi, Ja Wook Koo [Front Psychiatry (2022) ] Abstract
61	Metabotropic Glutamate Receptor 5 in Amygdala Target Neurons Regulates Susceptibility to Chronic Social Stress Jeongseop Kim, Shinwoo Kang, Tae-Yong Choi, Keun-A Chang, Ja Wook Koo [Biol Psychiatry (2022) ] Abstract
60	The Aftermath: Post-pandemic Psychiatric Implications of the COVID-19 Pandemic, a South Korean Perspective Sooyeon Min, Yun Ha Jeong, Jeongyeon Kim, Ja Wook Koo, Yong Min Ahn [Front Psychiatry (2021) ] Abstract
59	Relationship between Resting-State Alpha Coherence and Cognitive Control in Individuals with Internet Gaming Disorder: A Multimodal Approach Based on Resting-State Electroencephalography and Event-Related Potentials Park M, Yoo SY, Lee J, Koo JW, Kang UG, Choi J [Brain Sciences (2021) ] Abstract
58	A role of anterior cingulate cortex in the emergence of worker-parasite relationship Ahn S, Kang Y, Lee JW, Jeong SJ, Lee YJ, Lee S, Kim J, Koo JW#, Kim JJ#, Jung MW# [Proc Natl Acad Sci U S A (2021) ] Abstract
57	Problematic Use of Alcohol and Online Gaming as Coping Strategies during the COVID-19 Pandemic: A Mini Review Xu S, Park M, Kang UG, Choi JS, Koo JW* [Front Psychiatry (2021) ] Abstract
56	Social isolation impairs the prefrontal-nucleus accumbens circuit subserving social recognition in mice Park G, Ryu C, Kim S, Jeong SJ, Koo JW, Lee YS, Kim SJ [Cell Rep (2021) ] Abstract
55	Event-related brain response to visual cues in individuals with Internet gaming disorder: relevance to attentional bias and decision-making Kim BM, Lee J, Choi AR, Chung SJ, Park M, Koo JW, Kang UG, Choi JS [Transl Psychiatry (2021) ] Abstract
54	How stress shapes neuroimmune function: implications for the neurobiology of psychiatric disorders Koo JW, Wohleb ES [Biol Psychiatry (2021) ] Abstract
53	Comparison of the sensitizing effects of cocaine and ethanol on histone deacetylase isoforms in the rat brain Xu S, Koo JW, Kang UG [Neuroreport (2021) ] Abstract
52	Mental disorders linked to crosstalk between the gut microbiome and the brain Choi T-Y, Choi YP, Koo JW [Exp Neurobiol (2020) ] Abstract
51	Dopaminergic regulation of nucleus accumbens cholinergic interneurons demarcates susceptibility to cocaine addiction Lee J, Ribeiro E, Kim J, Ko B, Kronman HG, Jeong YH, Kim JK, Janak PH, Nestler EJ, Koo JW, Kim J-H* [Biol Psychiatry (2020) ] Abstract
50	Posterior parietal cortex mediates fear renewal in a novel context Joo B, Koo JW, S Lee [Molecular Brain (2020) ] Abstract
49	Repeated ethanol exposure influences key enzymes in cholesterol and lipid homeostasis via the AMPK pathway in the rat prefrontal corte Xu S, Jeong SJ, Li G, Koo JW, Kang UG [Alcohol (2020) ] Abstract
48	Role of Mesolimbic Brain-Derived Neurotrophic Factor in Depression Koo JW, Chaudhury D, Han MH, Nestler EJ [Biol Psychiatry (2019) ] Abstract
47	ALWPs improve cognitive function and regulate Aβ plaque and tau hyperphosphorylation in a mouse model of Alzheimer’s disease Lee J, Nam YP, Joo B*, Han K, Cho H, Koh YH, Koo JW, Kim J#, We Y#, Hoe H# [Front Mol Neurosci (2019) ] Abstract
46	Gadd45b mediates depressive-like role through DNA demethylation Labonte B, Jeong YH, Engmann O, Parise E, Issler O, Nestler EJ, Koo JW [Sci Rep (2019) ] Abstract
45	Viral Labeling of Neurons Synaptically Connected to Nucleus Accumbens Somatostatin Interneurons Ribeiro EA, Nectow AR, Pomeranz LE, Ekstrand MI, Koo JW, Bagot RC, Nestler EJ [Plos One (2019) ] Abstract
44	Korea Brain Initiative: Emerging Issues and Institutionalization of Neuroethics Jeong SJ, Lee IY, Jun BO, Ryu YJ, Sohn JW, Kim SP, Woo CW, Koo JW, Cho IJ, Oh U, Kim K, Suh PG [Neuron (2019) ] Abstract
43	An aqueous extract of herbal medicine ALWPs enhances cognitive performance and inhibits LPS-induced neuroinflammation via FAK/NF-kB signaling pathways Lee J* , Joo B*, Nam JH, Lee W, Nam HY, Seo Y, Kang H, Cho H, Jang YP, Kim J, We Y#, Koo JW#, Hoe H# [Front Aging Neurosci (2018) ] Abstract
42	Cocaine self-administration alters transcriptome-wide responses in the brain's reward circuitry Walker DM, Cates HM, Loh YE, Purushothaman I, Ramakrishnan A, Cahill ME, Lardner CK, Godino A, Kronman HG, Rabkin J, Lorsch Z, Mews P, Doyle MA, Feng J, Labonte B, Koo JW, Bagot RC, Seney ML, Logan RW, Calipari ES, Shen L, Nestler EJ [Biol Psychiatry (2018) ] Abstract
41	Transcriptional and Physiological Adaptations in Nucleus Accumbens Somatostatin Interneurons That Regulate Behavioral Responses to Cocaine Ribeiro E, Salery M, Scarpa JS, Calipari ES, Hamilton PJ, Ku S, Kronman HG, Purushothaman I, Juarez B, Heshmati M, Doyle MA, Lardner CK, Burek D, Strat A, Pirpinias S, Mouzon E, Han MH, Neve RL, Bagot RC, Kasarskis A, Koo JW, Nestler EJ [Nat Commun (2018) ] Abstract
40	Brain-Derived Neurotrophic Factor in the Mesolimbic Reward Circuitry Mediates Nociception in Chronic Neuropathic Pain. Zhang H, Qian YL, Li C, Liu D, Wang L, Wang XY, Liu MJ, Liu H, Zhang S, Guo XY, Yang JX, Ding HL, Koo JW, Mouzon E, Deisseroth K, Nestler EJ, Zachariou V, Han MH, Cao JL [Biol Psychiatry (2017) ] Abstract
39	Korea Brain Initiative: Integration and Control of Brain Functions. Jeong SJ, Lee H, Hur EM, Choe Y, Koo JW, Rah JC, Lee KJ, Lim HH, Sun W, Moon C, Kim K [Neuron (2016) ] Abstract
38	Essential Role of Mesolimbic Brain-Derived Neurotrophic Factor in Chronic Social Stress-Induced Depressive Behaviors. Koo JW, Labonte B, Engmann O, Calipari ES, Lorsch Z, Juarez B, Friedman AK, Walsh JJ, Han MH, Nestler EJ [Biol Psychiatry (2016) ] Abstract
37	Mesolimbic reward circuit mediates neuropathic thermal hyperalgesia via BDNF signaling. Zhang H, Li C, Qian YL. Liu H, Liu D, Zhang S, Guo XY, Ding HL, Liu MJ, Koo JW, Mouzon E, Nestler EJ, Zachariou V, Han MH, Cao JL [J Neurosci (2016) ] Abstract
36	BAZ1B in nucleus accumbens regulates reward-related behaviors in response to distinct emotional stimuli. Sun H, Martin JA, Werner CT, Wang Z-J, Scobie KN, Damez-Werno D, Shao N, Dias C, Rabkin J, Koo JW, Gancarz A, Mouzon E, Neve RL, Shen L, Dietz DM, Nestler EJ [J Neurosci (2016) ] Abstract
35	Bidirectional Synaptic Structural Plasticity after Chronic Cocaine Administration Occurs through Rap1 Small GTPase Signaling. Cahill ME, Bagot RC, Gancarz AM, Walker DM, Sun H, Wang ZJ, Heller EA, Feng J, Kennedy PJ, Koo JW, Cates HM, Neve RL, Shen L, Dietz DM, Nestler EJ [Neuron (2016) ] Abstract
34	Sex differences in nucleus accumbens transcriptome profiles associated with susceptibility versus resilience to sub-chronic variable stress. Hodes GE, Pfau ML, Purushothaman I, Ahn HF, Golden SA, Christoffel DJ, Magida J, Brancato A, Takahashi A, Flanigan ME, Menard C, Aleyasin H, Koo JW, Lorsch Z, Feng J, Heshmati M, Wang M, Turecki G, Neve RL, Zhang B, Shen L, Nestler EJ, Russo SJ [J Neurosci (2015) ] Abstract
33	ACF chromatin-remodeling complex mediates stress-induced depressive-like behavior. Sun H, Damez-Werno D, Scobie KN, Shao N, Dias C, Koo JW, Rabkin J, Maze I, Pena CJ, Korb E, Bagot RC, Cahill ME, Mouzon E, Heller EA, Cates H, Neve RL, Kennedy PJ, Dietz DM, Allis CD, Varga-Weisz P, Tamminga CA, Shen L, Nestler EJ [Nat Med (2015) ] Abstract
32	Cocaine induced 5hmC dynamics in mouse nucleus accumbens. Feng J, Shao NY, Szulwach K, Vialou VF, Huynh J, Zhong C, Le T, Ferguson D, Cahill ME, Li Y, Koo JW, Riberio E, Labonte B, Laitman B, Estey D, Stockman V, Kennedy PJ, Courousse T, Mensah I, Turecki G, Faull K, Song H, Fan G, Casaccia P, Shen L, Jin P, Nes [Nat Neurosci (2015) ] Abstract
31	Epigenetic basis of opiate suppression of Bdnf gene expression in the ventral tegmental area. Koo JW, Mazei-Robison MS, LaPlant Q, Egervari G, Braunscheidel KM, Adank DN, Ferguson D, Feng J, Sun H, Scobie KN, Damez-Werno D, Riberio E, Pena CJ, Walker D, Bagot RC, Cahill ME, Anderson SA, Labonte B, Hodes GE, Browne H, Chadwick B, Robison AJ, Vialou [Nat Neurosci (2015) ] Abstract
30	Loss of D1-specific NAc BDNF signaling enhances morphine reward by reduction of GABA inhibition. Koo JW, Lobo MK, Chaudhury D, Labonte B, Friedman AK, Heller EA, Pena CJ, Han MH, Nestler EJ [Neuropsychopharmacol (2014) ] Abstract
29	β-catenin mediates stress resilience through Dicer1/microRNA regulation. Dias C, Feng J, Sun H, Shao NY, Mazei-Robison MS, Damez-Werno D, Scobie K, Bagot R, LaBonte B, Ribeiro E, Liu X, Kennedy P, Vialou V, Ferguson D, Pena C, Calipari ES, Koo JW, Mouzon E, Ghose S, Tamminga C, Neve R, Shen L, Nestler EJ [Nature (2014) ] Abstract
28	Chronic cocaine-regulated epigenomic changes in mouse nucleus accumbens. Feng J, Wilkinson M, Ferguson D, Liu X, Purushothaman I, Ferguson D, Vialou VF, Maze I, Shao N, Kennedy PJ, Koo JW, Dias C, Laitman B, Stockman V, Laplant Q, Cahill M, Nestler EJ, Shen L [Genome Biology. (2014) ] Abstract
27	Nucleus Accumbens specific interventions in RGS9-2 activity modulate responses to morphine. Gaspari S, Papachatzaki MM, Koo JW, Carr FB, Tsimpanouli ME, Stergiou E, Bagot RC, Ferguson D, Mouzon E, Chacravarty S, Deisseroth K, Lobo MK, Zachariou V [Neuropsychopharmacol (2014) ] Abstract
26	Essential Role of Poly(ADP-Ribosyl)ation in Cocaine Action. Scobie KN, Damez-Werno D, Sun H, Shao N, Gancarz A, Panganiban CH, Dias C, Koo JW, Caiafa P, Kaufman L, Neve RL, Dietz DM, Shen L, Nestler EJ [PNAS (2014) ] Abstract
25	ΔFosB induction in prefrontal cortex by antipsychotic drugs is associated with negative behavioral outcomes. Dietz DM, Kennedy PJ, Sun H, Maze I, Gancarz AM, Vialou VF, Koo JW, Mouzon E, Ghose S, Tamminga CA, Nestler EJ [Neuropsychopharmacol (2014) ] Abstract
24	Stress and CRF gate neural activation of BDNF in the mesolimbic reward pathway. Walsh JJ, Friedman AK, Sun H, Heller EA, Ku S, Juarez B, Burnham VL, Mazei-Robison MS, Ferguson D, Golden SA, Koo JW, Chaudhury D, Christoffel DJ, Pomeranz L, Friedman JM, Russo SJ, Nestler EJ, Han MH [Nat Neurosci (2014) ] Abstract
23	ΔFosB Induction in Striatal Medium Spiny Neuron Subtypes in Response to Chronic Pharmacological, Emotional, and Optogenetic Stimuli. Lobo MK, Zaman S, Damez-Werno D, Koo JW, Bagot RC, DiNieri J, Nugent A, Finkel E, Chaudhury D, Chandra R, Riberio E, Rabkin J, Mouzon E, Cachope R, Cheer JF, Han MH, Dietz DM, Self DW, Hurd YL, Vialou VF, Eric Nestler EJ [J Neurosci (2013) ] Abstract
22	Essential Role of SIRT1 Signaling in the Nucleus Accumbens in Cocaine and Morphine Action. Ferguson D, Koo JW, Feng J, Heller EA, Rabkin J, Heshmati M, Renthal W, Neve RL, Li X, Shao N, Sartorelli V, Shen L, Nestler EJ [J Neurosci (2013) ] Abstract
21	Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. Chaudhury D, Walsh JJ, Friedman AK, Juarez B, Ku S, Koo JW, Ferguson D, Tsai H-C, Pomeranz L, Christoffel DJ, Nectow A, Ekstrand M, Domingos A, Mazei-Robison MS, Mouzon E, Lobo MK, Neve RL, Friedman JM, Russo SJ, Deisseroth K, Nestler EJ, Han MH [Nature (2013) ] Abstract
20	BDNF is a Negative Modulator of Morphine Action. Koo JW, Mazei-Robison MS, Chaudhury D, Juarez B, LaPlant Q, Ferguson D, Feng J, Sun H, Scobie KN, Damez-Werno D, Crumiller M, Ohnishi YN, Ohnishi YH, Mouzon E, Hodes GE, Dietz DM, Lobo MK, Neve RL, Russo SJ, Han MH, Nestler EJ [Science (2012) ] Abstract
19	Drug experience epigenetically primes fosB gene inducibility in rat nucleus accumbens. Damez-Werno D, LaPlant Q, Dietz DM, Sun H, Scobie KN, Walker IM, Koo JW, Vialou V, Mouzon E, Russo SJ, Nestler EJ [J Neurosci (2012) ] Abstract
18	Essential Role for Rac1 in Cocaine-Induced Structural Plasticity of Nucleus Accumbens Neurons. Dietz DM, Sun H, Lobo MK, Cahill ME, Chadwick B, Gao V, Koo JW, Mazei-Robison MS, Dias C, Maze I, Damez-Werno D, Dietz KC, Scobie KN, Ferguson D, Christoffel D, Ohnishi YH, Hodes GE, Zheng Y, Neve RL, Hahn KM, Russo SJ, Nestler EJ [Nat Neurosci (2012) ] Abstract
17	Role for mTOR signaling and neuronal activity in morphine-induced adaptations in ventral tegmental area dopamine neurons Mazei-Robison MS, Koo JW, Friedman AK, Lansink CS, Robison AJ, Vinish M, Krishnan V, Kim S, Siuta MA, Galli A, Niswender KD, Appasani R, Horvath MC, Neve RL, Worley PF, Snyder SH, Hurd YL, Cheer JF, Han MH, Russo SJ, Nestler EJ [Neuron (2011) ] Abstract
16	Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. LaPlant Q, Vialou V, Covington HE 3rd, Dumitriu D, Feng J, Warren BL, Maze I, Dietz DM, Watts EL, Iniguez SD, Koo JW, Mouzon E, Renthal W, Hollis F, Wang H, Noonan MA, Ren Y, Eisch AJ, Bolanos CA, Kabbaj M, Xiao G, Neve RL, Hurd YL, Oosting RS, Fan G, Mor [Nat Neurosci (2010) ] Abstract
15	Cell Type Specific Loss of BDNF Signaling Mimics Optogenetic Control of Cocaine Reward. Lobo MK, Covington HE 3rd, Chaudhury D, Friedman AK, Sun H, Damez-Werno D, Dietz DM, Zaman S, Koo JW, Kennedy PJ, Mouzon E, Mogri M, Neve RL, Deisseroth K, Han MH, Nestler EJ [Science (2010) ] Abstract
14	NF-kB a critical mediator of stress-impaired neurogenesis and depressive behavior. Koo JW, Russo SJ, Ferguson D, Nestler EJ, Duman RS [PNAS (2010) ] Abstract
13	Chronic treatment with AMPA receptor potentiator Org 26576 increases neuronal cell proliferation and survival in adult rodent hippocampus. Su XW, Li XY, Banasr M, Koo JW, Shahid M, Henry B, Duman RS [Psychopharmacology (Berl) (2009) ] Abstract
12	Evidence for IL-1 receptor blockade as a therapeutic strategy for the treatment of depression. Koo JW and Duman RS [Curr Opin Investig Drugs (2009) ] Abstract
11	Role of NF-kB in ovarian hormone-mediated stress hypersensitivity in females. LaPlant Q, Chakravarty S, Vialou V, Mukherjee S, Koo JW, Kalahasti G, Bradbury KR, Taylor SV, Maze I, Kumar A, Graham A, Birnbaum S, Krishnan V, Truong H-T, Neve RL, Nestler EJ, and Russo SJ [Biol Psychiatry (2009) ] Abstract
10	IL-1 receptor null mutant mice show decreased anxiety-like behavior and enhanced fear memory Koo JW and Duman RS [Neurosci Lett (2009) ] Abstract
9	IL-1β is an Essential Mediator of the Anti-Neurogenic and Anhedonic Effects of Stress. Koo JW and Duman RS [PNAS (2008) ] Abstract
8	Amygdalar Inactivation Blocks Stress-Induced Impairments in Hippocampal LTP and Spatial Memory. Kim JJ, Koo JW, Lee HJ, and Han J-S [J Neurosci (2005) ] Abstract
7	Selective Neurotoxic Lesions of Basolateral and Central Nuclei of the Amygdala Produce Differential Effects on Fear Conditioning. Koo JW, Han J-S, Kim JJ [J Neurosci (2004) ] Abstract
6	Postnatal environments can counteract prenatal effects on cognitive ability, cell proliferation, and synaptic protein expression. Koo JW, Park CH, Choi SH, Kim NJ, Choe JC, and Suh Y-H [FASEB J (2003) ] Abstract
5	General pharmacology of indole [2',3':3,4] pyrido [2,1-b] quinazolinium- 5,7,8,13-tetrahydro-14-methyl-5-oxo-chloride, a new anti-dementia agent. Park CH, Choi SH, Kim CH, Seo JH, Koo JW, Rah JC, Kim HS, Jeong SJ, Joo WS, Lee YJ, Kim YS, Kim MS, and Suh Y-H [Arzneimittelforschung (2003) ] Abstract
4	Oviposition preference for acorn size and offspring performance in Mechoris ursulus Roelofs (Coleoptera: Attelabidae) Koo JW, Roh HC, and Choe JC [J Ethol (2003) ] Abstract
3	Novel cognitive improving and neuroprotective activities of Polygala tenuifolia Willdenow extract, BT-11. Park CH, Choi SH, Koo JW, Kim H-S, Suh Y-H [Neurosci Res (2002) ] Abstract
2	Memory impairment and cholinergic dysfunction by centrally administered Aβ and carboxyl-terminal fragment of Alzheimer's APP in mice. Choi SH, Park CH, Koo JW, Seo JH, Kim HS, Jeong SJ, Lee JH, Kim SS, and Suh Y-H [FASEB J (2001) ] Abstract
1	Effects of nicotine on APP secretion and Aβ- or CT(105)-induced toxicity. Seo JH, Kim SS, Kim HS, Park CH, Jeong SJ, Lee JH, Choi SH, Chang KA, Rah JC, Koo JW, Kim EM, and Suh Y-H [Biol Psychiatry (2001) ] Abstract